Methods for the Phenotypic Detection of Extended Spectrum Beta Lactamase (ESBL)-Producing Bacteria

1983. These enzymes possess the ability to inactivate susceptible ?-lactam antibiotics i.e. penicillins, first, second and third generation cephalosporins aztreonam, but not cephamycins carbapenems . Their mode of action is by hydrolyzing ring. Even before first antibiotic (penicillin) was developed, resistance observed ESBL genes are plasmids- transposons- mediated, as such, can be spread easily other species bacteria. Resistance ESBL- producing bacteria a continuing cause public health problems , it increasingly being in community nosocomial acquired infections. Detection identification these ESBLs laboratory prime importance for selection appropriate used treatment infections caused The aim this review explain detail several phenotypic methods detection confirmation extended spectrum ? lactamases.
 Keywords: Antibiotic resistance, ESBL, bacteria, method